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The 404 1,149: Where everyone should get their Big Exit (podcast)
While we all patiently wait for Justin Yu's airline troubles to dissipate, CNET editors David Carnoy and Ty Pendlebury join Jeff on the show to chat about the world of self-publishing, the best places to find FLAC music, Microsoft Surface,Xbox Music, and the places you're most likely to break youriPhone. Topics from today's show:- Check out David's new book "The Big Exit." Or, for a chance to win a digital or hardcover copy, send an e-mail with "The Big Exit" in the subject line to the404 [at] cnet [dot] com. - Microsoft Surface dates and prices- Don't worry, theiPad Mini will come in just 24 easy-to-understand versions. - Xbox Music is coming. Don't call it Zune! - Ty's FLAC music-finding guide - Where you're most likely to break your iPhone. Be sure to follow David Carnoy and Ty Pendlebury on Twitter! Ep. 1149: Where everyone should get their Big Exit Episode marvel hero power leveling 1,149Listen Now:Download Today's PodcastSubscribe:iTunes (HD) |iTunes (SD) |iTunes (HQ) |iTunes (MP3) RSS (HD) |RSS (SD) |RSS (HQ) |RSS (MP3) Follow us on Twitter!The 404Jeff BakalarJustin Yu Add us on Facebook!The 404 Fan PageThe 404 GroupJustin YuJeff Bakalar
The 404 1,149: Where everyone should get their Big Exit (podcast)

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Google's Retain is new entrant when it comes to digital memo industry
Anyone who has ever jotted straight down a note at the back associated with envelope and additionally promptly lost it might be serious about Google's most recently released offering, Retain. The service facilitates users and keep checklists as well as voice hints, and annotate graphics. The digital memo industry is a engaging one plus the offering definitely will put Google and bing head to head together with services along the lines of Evernote. Experts predict of which Google will surely have entered industry a little too overdue. Memory aid providers are gorgeous a chord with purchasers and people who are very swamped as a result of information. Current sector leader Evernote features 15 mil active people. Microsoft has a very similar product . . . OneNote - where there are more compact rivals for instance Springpad and Grab. Now it seems Yahoo and google wants a sheet of the action. "Every day of the week we all find, hear and think of facts we need to don't forget. Usually we grab any pad regarding sticky insights, scribble a stern reminder and put that on the desktop, the freezer or fridge or the useful page to a magazine,Ins said Search engines software engineer Katherine Kuan in a content. Keep is Google attempt to go this ad-hoc notetaking straight into a more efficient online digital service. "With Prevent you can quickly jot ideas downward when you visualize them perhaps even include check-lists and snap shots to keep at the what's imperative that you you,Inch she further. The information is saved in Google Hard drive. Users could also speak memorandums and Keep transcribes it. And there is a seek out facility for anyone to locate what they are searching for. Currently Keep exists only through the web and / or as an instance for cellular phones and tablets running Android operating system 4.Zero or above. '800lb gorilla' But using little to tell apart it with competitors, a handful of feel Yahoo may find it hard to make a direct impact. "My gut gut instinct is that Msn may have are provided too late to the current. It has a historical past - by way of cloud products and social traffic - with coming already happened and can not make an impact," claimed Chris Environmentally friendly, principal technologies analyst from Davies Murphy Group. "But, if anyone can make a direct effect, it will be Google and yahoo," she or he added. "If you will find a 800lb gorilla like The search engines behind you will you are going to worry. Evernote cannot snooze on it's laurels but it gives you a huge users list and they are never assume all going to wilderness it marvel hero power leveling immediate." Tony Cripps, analyst by research service provider Ovum, perceives Google may well benefit from the proven fact that many now use her myriad solutions. "If you are a changed Google person it presents a good option. There exists a level of advantage about having access to a range of services using one log-in,Within he said. "I utilize Evernote but I most certainly will give mtss is a spin and then judge if it is employed by me.Inch
Google's Sustain is new entrant inside digital memo sell

marvel hero power leveling brussels diamond robber

Brussels usually robbery netting 'gigantic' haul
Informed robbers are making off with your "gigantic" haul with diamonds from a rapid raid within Brussels Flight terminal. Disguised as police officers, they fell apart through a boundary on Monday evening plus broke to the cargo on the Swiss-bound plane to accept the gems, anticipated to be really worth $50m (£32m; 37m euros). They fugitive back using it marvel hero power leveling . hole. Law enforcement later came across a burned-out truck close to the international airport. Police are looking for 10 men, a real prosecutors' spokeswoman suggested. Caroline De Hair, of the Antwerp Globe Diamond Middle, estimated all the haul for $50m, saying: "What i am talking about is perhaps a gigantic amount." Earlier experiences suggested any figure being higher * with the Belgian assert broadcaster reportedly placing it from 350m euros ($468m). AFP quotes an un-named spokeswoman from the same Antwerp center calling all the robbery "one in the biggest" ever. She announced that the diamond rings were "rough stones" getting transported as a result of Antwerp to Zurich. Antwerp certainly is the hub world wide diamond swap - around 150m euros' worth of diamonds move in and then out of the community every day, a spokeswoman increased. 'Professionals' Brussels prosecutor's spokeswoman Anja Bijnens stated the crooks were bad and most certainly armed, as well as used not one but two black cars or trucks with law enforcement markings. The caused their process through stability barriers not to mention sped towards the Helvetic Air route plane intending to take off - forcing open up the load to reach diamonds that had happened to be loaded about. The thieves had 120 services - not many of the shipment, she stated. No shots are fired together with no-one was injure. The raid appeared to be over in a few moments, and the criminals made away into the afternoon. They were "professionals", Milliseconds Bijnens said. Ms S Wolf says the raid would have been a blow towards Antwerp's reputation as the secure together with discreet stone centre. "This is causing quite some unrest,'' she said, as reported by AP current information agency. "It is incredible information on how easy everthing went. This is often worrying concerning competitiveness, ever since other gem centres want to pounce and control our status.'' An flight terminal spokesman, July Van Der Crujsse, could hardly explain the protection breach. "We stick to the most stern rules,'' he said.
Brussels engagement robbery fabric tailgate enclosures 'gigantic' haul

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Cold weather payments in May hit £4m, pronounces DWP
Four million excess weight in frigid weather payments to help vulnerable persons pay bills are actually made in Next month, compared with barely any in Goal 2012. Cold climatic conditions payments head over to those on Pension plan Credit and a lot of other income-related perks. Each seven-day quantity freezing environment results in an automated payment of £25 to a candidate people. The installments indicate the actual in temperatures compared with the first spring from 2012. Payment spaces Large swathes of the English are subjected to snow cautions, and A person,000 institutions are turn. The marvel hero power leveling payments, given by the Division for Deliver the results and Pensions, are aimed toward ensuring vulnerable and open people ( blank ) especially the seniors - ordinarily are not tempted to keep heating out because of budgetary worries. Areas which happen to have seen the instalments triggered soon are: Sennybridge within Wales, Bainbridge in Northern Yorkshire, Bingley in Western side Yorkshire, Lake Vyrnwy when it comes to Wales, Leek inside Staffordshire, as well as Tulloch Connect, Aviemore, Braemar, and Loch Glascarnoch with the Highlands. Continue reading the most important storyPayments triggered moscow and rome week Sennybridge when it comes to Wales, Bainbridge in South Yorkshire, Bingley in West Yorkshire, Lake Vyrnwy within Wales, Leek for Staffordshire, Tulloch Bridge, Aviemore, Braemar, in addition to Loch Glascarnoch in the Highlands, Eskdalemuir within the Scottish Borders, Fylingdales with North Yorkshire, Redesdale on North Tyneside, Salsburgh for North Lanarkshire, Shap in Cumbria, and then Aboyne in Aberdeenshire Other places where payments had been made in one more seven days encompass Eskdalemuir in the Scottish Edges, Fylingdales in West Yorkshire, Redesdale in To the north Tyneside, Salsburgh in East Lanarkshire, Shap throughout Cumbria, and Aboyne throughout Aberdeenshire. After the fee is induced it takes Ten days for the £25 to attain accounts. That cut-off point regarding payments is without a doubt 31 Drive, so if the actual cold tap out continues in April, all of these payments will never be made. In spite of this, around 3.5m pensioners are at a disadvantage as a result of not necessarily claiming Old age Credit whilst they are having difficulties on low incomes. You need to put in a Pensionable Credit maintain in order to obtain payments. Cold climate payments a long way this winter time stand at £138.5m, paid to almost 3.Several million families. This is by means of the total with £129m last winter. But it is even so well wanting 2010-11, when £430m appeared to be distributed. Pensions Reverend Steve Webb talked about: "I want to make sure of the most insecure people learn about the support that's available to them, within the surprisingly late cold time. "Cold weather monthly payments of £25 supply real guidance when the temperatures bites. To cold weather envisioned in the next week people must not have to worry about showing the home heating when temps plummet."
Cold weather funds in Drive hit £4m, pronounces DWP

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Down's syndrome 'linked that will brain meat loss'
A lack of your protein within Down's syndrome common sense could be the reason behind learning along with memory issues, says a US study. Writing naturally Medicine, Californian researchers found out that the extra replicate of chromosome 11 in of those that have the condition stimulated the meat loss. Their exploration found mending the meat in Down's disease mice improved upon cognitive operate and behaviour. The Down's Malady Association says the study had been interesting nevertheless causes of Down's are very confusing. Prof Huaxi Xu, senior publisher of the study the Sanford-Burnham Scientific research Institute, testified that in reports on rats they discovered your SNX27 protein was in fact important for brain function and memory space formation. Continue reading through the main story“Launch QuoteIn Down's syndrome, all of us lack of SNX27 is at least in some measure to blame for educational and cognitive defects.”Stop QuoteProf Huaxi XuSanford-Burnham Medical Research Company Mice with considerably less SNX27 had a fewer number of active glutamate receptors and for that reason had affected learning and even memory. The SNX27-deficient rats shared a few characteristics using Down's syndrome, hence the researchers looked over human intelligence with the disorder. This established their collected information in the science lab - that marvel hero power leveling individuals with Down's syndrome will have significantly lower levels of SNX27. Neurons on a normal mouse button (left) are generally longer not to mention fuller as compared to neurons from the mouse incomplete SNX27 (right) "So, on Down's syndrome, we all lack of SNX27 reaches least partially to blame for developing and intellectual defects," Prof Xu said. In all the lab, the studies team increased the levels with the protein within mice brains to see if the challenge could be remedied. "Everything goes back on track after SNX27 treatment plan," says Xin Wang, a grad member of the published information team. "First there are the glutamate receptors come, then memory deficit is usually repaired in our Down's syndrome rodents." But Prof Xu wary that scientific disciplines still had work to do to develop a safe technique of giving genes into the human brain. Ethical questions The researchers are now screening tiny molecules to look for those that may well increase SNX27 production or do the job in the brain. Carol Little boys, chief executive belonging to the Down's Syndrome Connections, said they were following the continuing growth of many biomedical studies into Down's disorder with fascination. "This particular analysis is of interest; on the other hand, the genetic causes of Down's situation are very complicated and we are nevertheless a long way away belonging to the development of medical treatments which can lead to improvement to cognition in of those that have Down's syndrome.Inch She moreover said these people were mindful of the ethical circumstances such remedies might boost for people with Down's symptoms and their households.
Down's syndrome 'linked to help you brain required protein loss'


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